Soft Computing in Bioinformatics
نویسنده
چکیده
s GO annotations Exession Me thy lat ion Keller/Popescu Tutorial 20 Sequence Comparison: Definitions • Sequence alignment: – A one-to-one matching of two sequences so that each character in a pair of sequences is associated with a single character of the other sequence or with a null character (gap) • Types of alignment: – Pair-wise vs. multiple – Global vs. local – Gapped vs ungapped • Homologous proteins: share a common ancestor – Orthologous: differ because they are found in different species – Paralogous: differ due to a gene duplication event -AGGCTATCACCTGACCTCCAGGCCGA--TGCCC--|| ||||||| |||| | || ||| ||||| TAG-CTATCAC--GACCGC--GGTCGATTTGCCCGAC
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